You are viewing an incomplete version of our website. Please click to reload the website as full version.

FMN1 anticorps (Formin 1) (HRP)

Détail du produit anti-FMN1 anticorps No. ABIN1712052, Fournisseur: Connectez-vous pour afficher
Antigène
  • si:dkey-81b15.10
  • fmn
  • formin
  • FMN
  • LD
  • BB164513
  • Fmn
  • formin-1
  • ld
  • RGD1306349
  • RGD1310100
  • formin 1
  • fmn1
  • FMN1
  • Fmn1
Alternatives
anti-Humain FMN1 anticorps pour Western Blotting
Reactivité
Humain, Souris, Rat (Rattus)
24
15
15
Hôte
Lapin
21
4
Clonalité
Polyclonal
Conjugué
Cet anticorp FMN1 est conjugé à/à la HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
13
9
5
2
2
1
1
1
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Request

Ce produit gratuit

Envoyez-nous votre proposition de validation. J'aimerais valider ce produit

Savoir plus

Immunogène KLH conjugated synthetic peptide derived from human FMN1/Formin 1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Fmn1/Formin 1 (FMN1 Antibody Extrait)
Sujet

The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.


Synonyms: FMN, Formin 1, Formin1, Formin-1, LD, Limb deformity protein homolog, FMN1_HUMAN.
ID gène 342184
Pathways Regulation of Actin Filament Polymerization
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months