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Guanylate Cyclase Activator 1A (Retina) (GUCA1A) anticorps (HRP)

Détails pour le produit réf. ABIN1712059, Fournisseur: Connectez-vous pour afficher
Antigène
  • MGC84170
  • GUCA1A
  • guca1a
  • MGC146317
  • C6orf131
  • COD3
  • CORD14
  • GCAP
  • GCAP1
  • GUCA
  • GUCA1
  • dJ139D8.6
  • GC-A
  • Gcap1
  • Guca1
  • mGCAP1
  • guanylate cyclase activator 1A (retina)
  • guanylate cyclase activator 1a (retina)
  • guanylate cyclase activator 1C
  • guca1a
  • GUCA1A
  • LOC100224057
  • Guca1a
  • GUCA1C
Alternatives
anti-Humain Guanylate Cyclase Activator 1A (Retina) anticorps pour Western Blotting
Reactivité
Humain, Souris, Rat (Rattus)
56
24
24
2
2
1
1
1
1
1
1
Hôte
Lapin
51
5
Clonalité
Polyclonal
Conjugué
HRP
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
36
25
15
13
7
2
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human GCAP1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gcap1 (GUCA1A Antibody Extrait)
Sujet

intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90 % similar, consisting of 201 to 205 amino acids, and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event.


Synonyms: COD3, GCAP 1, GCAP, Guanylate Cyclase Activating Protein Photoreceptor 1, Guanylate Cyclase Activating Protein Photoreceptor 1, Guanylate Cyclase Activator 1A, Guanylate Cyclase Activator 1A, Guanylin 1, Guanylin 1, guanylyl cyclase activating protein 1, Guanylyl cyclase-activating protein 1, GUC1A_HUMAN, GUCA, GUCA1, GUCA1A, GUCA1A.
ID gène 2978
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months