Glutamate Dehydrogenase 2 (GLUD2) anticorps (HRP)

Détails pour le produit réf. ABIN1712065, Fournisseur: Connectez-vous pour afficher
Antigène
  • GDH2
  • GLUDP1
  • GLUTAMATE DEHYDROGENASE 2
  • T2I1.150
  • T2I1_150
  • glutamate dehydrogenase 2
  • EG545999
  • Glud-2
  • Glud2
  • Gm5902
  • GluD2
  • glutamate dehydrogenase 2
  • glutamate dehydrogenase, pseudogene
  • glutamate receptor, ionotropic, delta 2
  • gdhA_2
  • GLUD2
  • GDH2
  • Glud-ps
  • Grid2
Reactivité
Humain, Souris, Rat (Rattus)
62
22
22
1
1
1
1
1
Hôte
Lapin
55
7
Clonalité
Polyclonal
Conjugué
HRP
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
49
25
13
13
6
6
2
2
1
1
1
1
Options
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic peptide derived from human GLUD2
Isotype IgG
Purification Purified by Protein A.
Autre désignation Glud2 (GLUD2 Antibody Extrait)
Sujet

GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.

Subcellular location: Extracellular

Synonyms: GDH 2, GDH, GDH2, GLUDP1, Glutamate dehydrogenase 2, Glutamate dehydrogenase 2 mitochondrial, Glutamate dehydrogenase pseudogene 1.

ID gène 2747
Domaine de recherche Metabolism, Amino Acids
Pathways Synaptic Membrane
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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