VGF anticorps (VGF Nerve Growth Factor Inducible) (HRP)

Details for Product anti-VGF Antibody No. ABIN1712081, Fournisseur: Connectez-vous pour afficher
Antigène
  • VGF
  • Gm1052
  • VGF nerve growth factor inducible
  • neurosecretory protein VGF-like
  • VGF
  • LOC618042
  • Vgf
Alternatives
anti-Humain VGF anticorps pour Immunofluorescence (fixed cells)
Reactivité
Humain, Souris, Rat (Rattus)
88
66
62
5
3
2
2
1
1
1
1
Hôte
Lapin
91
2
Clonalité
Polyclonal
Conjugué
Cet anticorp VGF est conjugé à/à la HRP
6
6
3
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
50
34
26
25
23
5
5
2
2
2
1
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from human NERP2
Isotype IgG
Purification Purified by Protein A.
Autre désignation VGF/NERP2 (VGF Antibody Extrait)
Sujet

This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.

Subcellular location: Nucleus

Synonyms: NERP-2, Nerve growth factor inducible, Neuroendocrine regulatory peptide-2, Neurosecretory protein VGF, VGF, VGF_HUMAN.

ID gène 7425
Pathways Hormone Transport, Carbohydrate Homeostasis
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months