NAE1 anticorps (NEDD8 Activating Enzyme E1 Subunit 1) (HRP)

Details for Product anti-NAE1 Antibody No. ABIN1712107, Fournisseur: Connectez-vous pour afficher
Antigène
  • APPBP1
  • CG7828
  • Dmel\\CG7828
  • anon-WO0140519.225
  • dAPP-BP1
  • dAPPBP1
  • A-116A10.1
  • ula-1
  • Appbp1
  • 59kDa
  • appbp1
  • zgc:66148
  • beta-Amyloid precursor protein binding protein 1
  • NEDD8 activating enzyme E1 subunit 1
  • nedd8 activating enzyme E1 subunit 1
  • Protein ULA-1
  • APP-BP1
  • NAE1
  • Nae1
  • nae1
  • ula-1
Reactivité
Humain, Souris, Rat (Rattus)
103
31
29
3
1
1
1
1
1
Hôte
Lapin
82
22
Clonalité
Polyclonal
Conjugué
Cet anticorp NAE1 est conjugé à/à la HRP
5
5
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
87
40
34
17
13
3
2
2
1
Options
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic peptide derived from human APPBP1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Appbp1 (NAE1 Antibody Extrait)
Sujet

Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.

Subcellular location: Cell membrane

Synonyms: HPP1, ula-1, APPBP1, A-116A10.1, NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1

ID gène 8883
UniProt Q13564
Domaine de recherche Proteolysis / Ubiquitin
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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