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GEM Interacting Protein (GMIP) anticorps (HRP)

Détails pour le produit réf. ABIN1712139, Fournisseur: Connectez-vous pour afficher
Antigène
  • MGC80729
  • ARHGAP46
  • 5031419I10Rik
  • RGD1565577
  • GEM interacting protein
  • Gem-interacting protein
  • GMIP
  • gmip
  • Gmip
Reactivité
Humain, Souris, Rat (Rattus)
21
14
14
1
1
1
1
Hôte
Lapin
21
Clonalité
Polyclonal
Conjugué
HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
13
6
5
2
1
1
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human GMIP
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gmip (GMIP Antibody Extrait)
Sujet

The Rho family of GTP-binding proteins plays a role in the development of neuronal structure. The activation of the GTP-bound form is regulated by GTPase-activating proteins, which stimulate GTP hydrolysis, leading to inactivation. GMIP (Gem-interacting protein) is a 970 amino acid protein that stimulates the GTPase activity of RhoA in vitro and in vivo. GMIP interacts with Gem through its N-terminus and has a Rho GTPase-activating protein domain at its C-terminus. GMIP is able to inhibit RhoA function, leading to Actin cytoskeletal reorganization in vivo. Encoded by a gene that maps to human chromosome 19p13.11, GMIP contains one phorbol-ester/DAG-type zinc finger and one Rho-GAP domain.


Synonyms: ARHGAP46, GEM interacting protein.
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months