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delta 1 Catenin (pSer268) anticorps (HRP)

Détails pour le produit réf. ABIN1712156, Fournisseur: Connectez-vous pour afficher
Antigène
Épitope
pSer268
15
15
15
14
1
1
Reactivité
Humain, Souris, Rat (Rattus)
61
44
44
Hôte
Lapin
61
Clonalité
Polyclonal
Conjugué
HRP
4
4
4
4
4
4
4
4
4
4
4
4
4
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
54
13
13
Options
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Immunogène KLH conjugated synthetic phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Ser268
Isotype IgG
Purification Purified by Protein A.
Sujet

Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.


Synonyms: delta 1 Catenin phospho S268, p-delta 1 Catenin phospho S268, Cadherin associated Src substrate, Cadherin-associated Src substrate, CAS, Catenin cadherin associated protein delta 1, Catenin delta 1, Catenin delta-1, CTND1_HUMAN, CTNND 1, CTNND, CTNND1, KIAA0384, p120, P120 CAS, p120 catenin, P120 CTN, p120cas, p120ctn, P120CAS, P120CTN.
ID gène 1500
Domaine de recherche Stem Cells, Wnt, Cytoskeleton, Microfilaments
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months