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GATA4 anticorps (GATA Binding Protein 4) (pSer105) (HRP)

Détail du produit anti-GATA4 anticorps No. ABIN1712159, Fournisseur: Connectez-vous pour afficher
Antigène
  • gata-4
  • xgata4
  • xGATA-4
  • MGC81427
  • GATA4
  • GATA-4
  • Gata4
  • gata4
  • ASD2
  • VSD1
  • Gata-4
  • gata
  • GATA binding protein 4
  • glutamyl-tRNA(Gln) amidotransferase subunit A
  • GATA-4 zinc-finger transcription factor
  • gata4 transcription factor
  • GATA4
  • GATA-binding protein 4
  • LOC100230031
  • gata4
  • GATA4
  • gatA4
  • GATA-4
  • LOC100534420
  • Gata4
  • gata4-b
Alternatives
anti-Humain GATA4 anticorps pour Western Blotting
Épitope
pSer105
22
15
12
9
9
7
6
5
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
185
132
105
11
8
3
3
3
2
2
1
1
1
Hôte
Lapin
136
32
22
2
Clonalité
Polyclonal
Conjugué
Cet anticorp GATA4 est conjugé à/à la HRP
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
151
62
42
27
24
21
17
7
6
3
2
2
1
1
Options
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Immunogène KLH conjugated synthetic phosphopeptide derived from human GATA4 around the phosphorylation site of Ser105
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gata4 (GATA4 Antibody Extrait)
Sujet

Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.


Synonyms: GATA4 phospho S105, p-GATA-4Ser 105, p-GATA-4Ser105, GATA binding factor 4, GATA 4, GATA4, GATA-4, Transcription factor GATA-4, GATA-binding factor 4, Gata4, GATA4_HUMAN, GATA-binding factor 4.
ID gène 2626
Domaine de recherche Hypertrophy, Lineage Markers, Transcription Factors
Pathways Peptide Hormone Metabolism, Carbohydrate Homeostasis
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months