Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1) anticorps (HRP)

Détails pour le produit réf. ABIN1712166, Fournisseur: Connectez-vous pour afficher
Antigène
  • AIPL1
  • lca4
  • aipl2
  • AIPL2
  • LCA4
  • A930007I01Rik
  • aryl hydrocarbon receptor interacting protein-like 1
  • aryl hydrocarbon receptor-interacting protein-like 1
  • AIPL1
  • aipl1
  • LOC100347082
  • Aipl1
Reactivité
Humain, Souris, Rat (Rattus)
87
35
29
2
2
1
1
1
1
Hôte
Lapin
61
26
Clonalité
Polyclonal
Conjugué
HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
67
37
34
22
19
13
11
5
4
3
1
1
1
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from human AIPL1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Aipl1 (AIPL1 Antibody Extrait)
Sujet

The inherited blindness associated protein, aryl hydrocarbon receptor interacting protein-like 1 (AIPL1), interacts with the cell cycle regulator protein NUB1. AIPL1 is crucial for protein folding and stabilization, as well as for protein trafficking. It localizes to the nucleus or cytoplasm and is highly expressed in the pineal gland and the retina. In the retina, AIPL1 is expressed in both developing cone and rod photoreceptors, but it is restricted to rod photoreceptors in the adult human retina. Defects in the gene encoding for AIPL1 can cause Leber congenital amaurosis type IV, an early-onset, inherited autosomal recessive disorder that results in childhood blindness.

Subcellular location: Cytoplasm, Nucleus

Synonyms: A930007I01Rik, Aipl1, AIPL1_HUMAN, AIPL2, Aryl hydrocarbon interacting protein like 1, Aryl hydrocarbon receptor interacting protein like 1, Aryl-hydrocarbon-interacting protein-like 1, LCA4, MGC25485, OTTHUMP00000128207, OTTMUSP00000006382, RP23-401C17.1.

ID gène 23746
Domaine de recherche Neurology
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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