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Boule anticorps (HRP)

Détails pour le produit réf. ABIN1712185, Fournisseur: Connectez-vous pour afficher
Antigène
  • BOULE
  • bol, boule-like (Drosophila)
  • boule
  • BOLL
  • LOC100155042
Reactivité
Humain, Souris, Rat (Rattus)
25
14
14
1
1
Hôte
Lapin
14
11
Clonalité
Polyclonal
Conjugué
HRP
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
13
10
2
2
2
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Immunogène KLH conjugated synthetic peptide derived from human BOULE
Isotype IgG
Purification Purified by Protein A.
Sujet

Spermatogenesis represents the intricate developmental process of mitotic and meiotic cell divisions that ultimately leads to the production of haploid spermatozoa. BOULE, a member of the human deleted in azoospermia (DAZ) family, functions as a key conserved switch that regulates the progression of germ cells through meiosis in man. BOULE is an RNA-binding protein that regulates the expression of twine, a Cdc25 phosphatase, which promotes progression through meiosis. BOULE is expressed not only in the testis, but also in the nervous system, where it may play a role in neural communication. Mutations in the BOULE gene are be associated with male infertility, and the relative proportions of the three BOULE isoforms (B1, B2 and B3) may function as predictive markers for meiotic efficiency.


Synonyms: Bol Drosophila boule homolog like, Bol, Bol boule like, Bol, boule like Drosophila, bol, boule-like Drosophila, Boll, BOLL_HUMAN, BOULE, Boule like, BOULE, Drosophila, homolog of, Protein boule like, Protein boule-like, Putative uncharacterized protein BOLL.
ID gène 66037
Domaine de recherche Chromatin and Nuclear Signaling, Chromatin Binding Proteins
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months