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C1ORF194 anticorps (Chromosome 1 Open Reading Frame 194) (HRP)

Détail du produit anti-C1ORF194 anticorps No. ABIN1712196, Fournisseur: Connectez-vous pour afficher
Antigène
  • chromosome 1 open reading frame 194
  • C1orf194
Reactivité
Humain, Souris, Rat (Rattus)
16
14
14
Hôte
Lapin
16
Clonalité
Polyclonal
Conjugué
Cet anticorp C1ORF194 est conjugé à/à la HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
13
4
3
2
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human C1orf194
Isotype IgG
Purification Purified by Protein A.
Autre désignation C1orf194
Sujet

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf194 gene product has been provisionally designated C1orf194 pending further characterization. There are two isoforms of C1orf194 that are produced as a result of alternative splicing events.


Synonyms: C1orf194, CA194_HUMAN, Chromosome 1 open reading frame 194, Hypothetical protein LOC1270032, OTTHUMP00000013446, OTTHUMP00000013448, Uncharacterized protein C1orf194.
ID gène 127003
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months