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CYP26A1 anticorps (AA 101-200) (HRP)

CYP26A1 Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712235
  • Antigène Voir toutes CYP26A1 Anticorps
    CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))
    Épitope
    • 14
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivité
    • 56
    • 21
    • 19
    • 4
    • 2
    • 2
    Humain
    Hôte
    • 55
    • 5
    • 1
    Lapin
    Clonalité
    • 49
    • 12
    Polyclonal
    Conjugué
    • 31
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CYP26A1 est conjugé à/à la HRP
    Application
    • 43
    • 18
    • 13
    • 13
    • 9
    • 8
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CYP26A1
    Isotype
    IgG
    Top Product
    Discover our top product CYP26A1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))
    Autre désignation
    CYP26A1 (CYP26A1 Produits)
    Synonymes
    anticorps CP26, anticorps CYP26, anticorps P450RAI, anticorps P450RAI1, anticorps Cyp26, anticorps P450RA, anticorps RAH, anticorps RACE, anticorps XCYP26A1, anticorps cyp26, anticorps xCYP26, anticorps cp26, anticorps p450rai, anticorps p450rai1, anticorps CYP26A, anticorps cb24, anticorps id:ibd5061, anticorps wu:fb81e05, anticorps cytochrome P450 family 26 subfamily A member 1, anticorps cytochrome P450, family 26, subfamily a, polypeptide 1, anticorps cytochrome P450 family 26 subfamily A member 1 S homeolog, anticorps cytochrome P450 family 26 subfamily A member 1 L homeolog, anticorps cytochrome P450, family 26, subfamily A, polypeptide 1, anticorps CYP26A1, anticorps Cyp26a1, anticorps cyp26a1.S, anticorps cyp26a1.L, anticorps cyp26a1
    Sujet

    Synonyms: CP26, CP26A_HUMAN, CYP26, CYP26A 1, cyp26a1, Cytochrome P450 26A1, Cytochrome P450 family 26 subfamily A polypeptide 1, Cytochrome P450 retinoic acid-inactivating 1, cytochrome P450, family 26, subfamily A, polypeptide 1, cytochrome P450, subfamily XXVIA, polypeptide 1, Cytochrome P450RAI, hP450RAI, OTTHUMP00000020102, OTTHUMP00000020103, P450, P450 retinoic acid inactivating 1, P450RAI, P450RAI1, Retinoic acid 4 hydroxylase, Retinoic acid 4-hydroxylase, Retinoic acid metabolizing cytochrome, Retinoic acid-metabolizing cytochrome.

    Background: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor 2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.

    ID gène
    1592
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Monocarboxylic Acid Catabolic Process
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