Polymerase (DNA Directed) kappa (POLK) anticorps (HRP)

Détails pour le produit réf. ABIN1712246, Fournisseur: Connectez-vous pour afficher
Antigène
  • POLK
  • DKFZp459J211
  • si:ch211-254o18.3
  • LAK-1
  • Pols
  • TRF4
  • TRF4-1
  • DINB1
  • DINP
  • POLQ
  • Dinb1
  • polymerase (DNA directed) kappa
  • DNA polymerase kappa
  • PAP associated domain containing 7
  • polymerase (DNA directed), kappa
  • POLK
  • polk
  • Tb11.01.0080
  • Tb11.01.0010
  • Tb11.01.0020
  • Tb11.01.0030
  • Tb11.01.0040
  • Tb11.01.0050
  • Tb11.12.0001
  • Tb11.12.0002
  • Tb11.12.0003
  • Papd7
  • Polk
Alternatives
anti-Humain Polymerase (DNA Directed) kappa anticorps pour Immunofluorescence (fixed cells)
Reactivité
Humain, Souris, Rat (Rattus)
90
28
26
4
4
4
4
4
2
1
1
1
1
Hôte
Lapin
61
20
9
Clonalité
Polyclonal
Conjugué
HRP
4
4
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
71
41
20
18
13
12
10
5
3
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK
Isotype IgG
Purification Purified by Protein A.
Autre désignation Dna Polymerase kappa/polk (POLK Antibody Extrait)
Sujet

DNA polymerase lambda (pol Kappa), also designated DNA polymerase Kappa or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol Kappa is a member of the DNA polymerase type-X family. Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol Kappa may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA.

Synonyms: DNA polymerase kappa, DINB protein, Short=DINP, POLK_HUMAN.

ID gène 51426
Pathways Réparation de l'ADN
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months