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SLC1A6 anticorps (AA 151-250) (HRP)

SLC1A6 Reactivité: Humain WB, ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712249
  • Antigène Voir toutes SLC1A6 Anticorps
    SLC1A6 (Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6))
    Épitope
    • 14
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivité
    • 44
    • 18
    • 11
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 3
    Lapin
    Clonalité
    • 43
    • 3
    Polyclonal
    Conjugué
    • 14
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLC1A6 est conjugé à/à la HRP
    Application
    • 30
    • 14
    • 13
    • 13
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EAAT4
    Isotype
    IgG
    Top Product
    Discover our top product SLC1A6 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SLC1A6 (Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6))
    Autre désignation
    EAAT4 (SLC1A6 Produits)
    Synonymes
    anticorps SLC1A6, anticorps zgc:171923, anticorps EAAT4, anticorps solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, anticorps solute carrier family 1 member 6, anticorps excitatory amino acid transporter 4-like, anticorps SLC1A6, anticorps slc1a6, anticorps LOC100224299, anticorps Slc1a6
    Sujet

    Synonyms: Excitatory amino acid transporter 4, High affinity neuronal glutamate transporter, MGC33092, MGC43671, Sodium dependent glutamate/aspartate transporter, Solute carrier family 1 high affinity aspartate/glutamate transporter member 6, Solute carrier family 1 member 6 ,EAA4_HUMAN.

    Background: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.

    ID gène
    6511
    UniProt
    P48664
    Pathways
    Dicarboxylic Acid Transport
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