PHC1 anticorps (AA 751-900) (HRP)

N° du produit ABIN1712250

Détail du produit anti-PHC1 anticorps (HRP)

Antigène: PHC1 (Polyhomeotic-Like 1 (PHC1))

Épitope: AA 751-900

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHC1 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EDR1/PHC1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PHC1

Antigène: PHC1 (Polyhomeotic-Like 1 (PHC1))

Autre désignation: EDR1/PHC1 (PHC1 Produits)

Synonymes: anticorps EDR1, anticorps HPH1, anticorps RAE28, anticorps AW557034, anticorps Edr, anticorps Edr1, anticorps Mph1, anticorps Rae-28, anticorps rae28, anticorps polyhomeotic homolog 1, anticorps polyhomeotic-like 1 (Drosophila), anticorps Phc1, anticorps PHC1

Sujet:

Synonyms: Early development regulatory protein 1, EDR1 PH1, hPH1, mPH1, PH1, Polyhomeotic-like protein 1, Rae28, PHC1_HUMAN.

Background: PHC1 is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.

ID gène: 1911