EYA3 anticorps (Eyes Absent Homolog 3 (Drosophila)) (HRP)

Details for Product anti-EYA3 Antibody No. ABIN1712263, Fournisseur: Connectez-vous pour afficher
Antigène
  • zgc:152966
  • si:ch211-195b13.2
  • Xeya3
  • MGC85199
  • EYA3
  • AI844637
  • eyes absent homolog 3
  • eyes absent homolog 3 (Drosophila)
  • eyes absent 3 homolog (Drosophila)
  • eya3
  • EYA3
  • Eya3
Alternatives
anti-Humain EYA3 anticorps pour Western Blotting
Reactivité
Humain, Souris, Rat (Rattus)
38
28
26
7
7
6
6
6
6
1
1
Hôte
Lapin
38
Clonalité
Polyclonal
Conjugué
Cet anticorp EYA3 est conjugé à/à la HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
20
13
9
9
5
5
4
2
Options
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Immunogène KLH conjugated synthetic peptide derived from human EYA3
Isotype IgG
Purification Purified by Protein A.
Autre désignation Eya3 (EYA3 Antibody Extrait)
Sujet

EYA3 is a 573 amino acid protein that localizes to both the nucleus and the cytoplasm and is one of several mammalian homologs of the Drosophila Eya (eyes absent) protein. Existing as two alternatively spliced isoforms, EYA3 possesses magnesium-catalyzed phosphatase activity and is thought to play a role in transcriptional regulation during organogenesis. Specifically, EYA3 interacts with proteins such as Six1 and, via this interaction, functions to activate the expression of genes that are involved in cellular proliferation and organ development. Upon DNA damage, EYA3 may be phosphorylated by ATM or ATR. The gene encoding EYA3 maps to chromosome 1, which spans about 260 million base pairs and comprises nearly 8 % of the human genome.

Synonyms: AI844637, DKFZp686C132, EYA3, EYA3_HUMAN, Eyes absent 3, Eyes absent 3 homolog Drosophila, Eyes absent homolog 3, OTTMUSP00000010370, RP11-460I13.4, RP23-442A20.1.

ID gène 2140
Domaine de recherche Stem Cells, Transcription Factors
Pathways Positive Regulation of Response to DNA Damage Stimulus
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months