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Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) anticorps (HRP)

Détails pour le produit réf. ABIN1712272, Fournisseur: Connectez-vous pour afficher
Antigène
  • p55-Fgr
  • SRC2
  • c-fgr
  • c-src2
  • p55c-fgr
  • p58-Fgr
  • p58c-fgr
  • Fibroblast growth factor receptor 1
  • Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • feline Gardner-Rasheed sarcoma viral oncogene
  • feline Gardner-Rasheed sarcoma viral oncogene homolog
  • Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog
  • Fgfr1
  • FGR
  • Fgr
Alternatives
anti-Humain Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog anticorps pour Western Blotting
Reactivité
Humain, Souris, Rat (Rattus)
113
57
31
3
2
1
1
1
1
Hôte
Lapin
77
31
19
Clonalité
Polyclonal
Conjugué
HRP
5
4
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
112
64
38
20
13
7
3
3
1
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human FGR/SRC2
Isotype IgG
Purification Purified by Protein A.
Autre désignation Fgr/Src2 (FGR Antibody Extrait)
Sujet

Src is the human homolog of the v-Src gene of the rous sarcoma virus, also designated avian sarcoma virus or ASV. Src was the first proto-oncogenic non-receptor tyrosine kinase characterized in human. The Src family, which has common structural motifs, is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src-family ki-nases contain an amino-terminal cell membrane anchor followed by an SH3 domain and an SH2 domain, which are involved in modular association and activation, respectively. Src-family kinases, which are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization and membrane trafficking. c-Fgr is a human non-receptor tyrosine kinase family member that was discovered by using a probe toward the v-Fgr portion of the cell-derived domain of Gardner-Rasheed feline sarcoma virus. The human c-Fgr gene encodes a 529 amino acid protein.


Synonyms: c fgr, c fgr protooncogene, c src 2 proto oncogene, c src2, FGR, FLJ43153, Gardner Rasheed feline sarcoma viral v fgr, Gardner Rasheed feline sarcoma viral v fgr oncogene homolog, MGC75096, p55 c fgr protein, P55 FGR, p55c fgr, p58c fgr, Proto oncogene c Fgr, Proto oncogene tyrosine protein kinase FGR, SRC 2, SRC2, Tyrosine protein kinase Fgr, FGR_HUMAN.
ID gène 2268
Pathways Sensory Perception of Sound, Stem Cell Maintenance, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months