Fibronectins are multi-domain glycoproteins that bind to a variety of substances including collagen, actin, heparin, DNA, fibrin and fibronectin receptors. They are involved in a diverse array of important functions such as blood coagulation, wound healing, cell adhesion, cell differentiation and migration. FNDC4 (Fibronectin type III domain-containing protein 4), also known as FRCP1 (Fibronectin type III repeat-containing protein 1), is a 234 amino acid membrane protein that contains one fibronectin type-III domain, which serves as a binding site for DNA, heparin or the cell surface. The gene encoding FNDC4 is localized to human chromosome two, which houses over 1,400 genes and comprises nearly 8 % of the human genome.
Subcellular location: Extracellular
Synonyms: Fibronectin type III domain containing 4, Fibronectin type III domain containing protein 4, Fibronectin type III domain-containing protein 4, Fibronectin type III repeat containing protein 1, Fibronectin type III repeat-containing protein 1, FLJ22362, FNDC 4, FNDC4, FNDC4_HUMAN, FRCP 1, FRCP1.