This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq, Dec 2009].
Synonyms: Drosphilia Forkhead Homolog Like 12, Drosphilia Forkhead Homolog Like 12, FKHL 12, FKHL 12, FKHL12, Forkhead Box E3, Forkhead Box E3, Forkhead Related Activator 8, Forkhead Related Activator 8, Forkhead related protein FKHL12, FOXE3 forkhead box E3, FREAC 8, FREAC 8, FREAC8, FOXE3_HUMAN.