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GPR124 anticorps (G Protein-Coupled Receptor 124) (HRP)

Détail du produit anti-GPR124 anticorps No. ABIN1712300, Fournisseur: Connectez-vous pour afficher
Antigène
  • MGC69043
  • si:dkey-208c22.2
  • TEM5
  • 8430414O08Rik
  • 9530074E10Rik
  • Tem5
  • mKIAA1531
  • GPR124
  • G protein-coupled receptor 124
  • G-protein coupled receptor 124-like
  • gpr124
  • GPR124
  • LOC100363275
  • Gpr124
  • LOC616111
Reactivité
Humain, Souris, Rat (Rattus)
75
29
24
2
2
2
2
2
2
1
Hôte
Lapin
66
9
Clonalité
Polyclonal
Conjugué
Cet anticorp GPR124 est conjugé à/à la HRP
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
25
24
24
21
14
9
8
2
1
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from human G protein coupled receptor 124
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gpr124/Tem5 (GPR124 Antibody Extrait)
Sujet

Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.

Subcellular location: Extracellular


Synonyms: DKFZp434C211, DKFZp434J0911, FLJ14390, G protein coupled receptor 124, G-protein coupled receptor 124, GP124_HUMAN, GPR 124, GPR124, KIAA1531, TEM 5, TEM5, Tumor endothelial marker 5, Tumor endothelial marker 5 precursor, GPCR GPR124.
ID gène 25960
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months