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GALNT13 anticorps (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 13 (GalNAc-T13)) (HRP)

Détail du produit anti-GALNT13 anticorps No. ABIN1712306, Fournisseur: Connectez-vous pour afficher
Antigène
  • si:ch1073-215b15.1
  • A230002A12
  • A230020F20
  • BB182356
  • GalNAc-T13
  • H_NH0187G20.1
  • WUGSC:H_NH0187G20.1
  • T13
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
  • GALNT13
  • galnt13
  • Galnt13
Reactivité
Humain, Souris, Rat (Rattus)
48
31
20
4
4
4
3
2
1
1
Hôte
Lapin
41
7
Clonalité
Polyclonal
Conjugué
Cet anticorp GALNT13 est conjugé à/à la HRP
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
34
19
13
3
1
1
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Immunogène KLH conjugated synthetic peptide derived from human GALNT13/GalNAc-T13
Isotype IgG
Purification Purified by Protein A.
Autre désignation Galnt13/Galnac-T13 (GALNT13 Antibody Extrait)
Sujet

The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells.


Synonyms: GalNAc T13, GalNAc transferase 13, N acetylgalactosaminyltransferase 13, Polypeptide GalNAc transferase 13, pp GaNTase 13, Protein UDP acetylgalactosaminyltransferase 13, UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13, UDP N acetyl alpha D galactosamine:polypeptide, GLT13_HUMAN.
ID gène 114805
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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