Hedgehog Acyltransferase-Like (HHATL) anticorps (HRP)

Détails pour le produit réf. ABIN1712346, Fournisseur: Connectez-vous pour afficher
Antigène
  • gup1
  • oact3
  • mboat3
  • MGC53261
  • mstp002
  • MGC89797
  • GUP1
  • C3orf3
  • MBOAT3
  • MSTP002
  • OACT3
  • 1110011D13Rik
  • Gup1
  • RGD1311911
  • hedgehog acyltransferase-like
  • hhatl
  • HHATL
  • LOC100336796
  • Hhatl
Alternatives
anti-Humain Hedgehog Acyltransferase-Like anticorps pour Western Blotting
Reactivité
Humain, Souris, Rat (Rattus)
24
19
19
Hôte
Lapin
23
1
Clonalité
Polyclonal
Conjugué
HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
13
9
6
5
5
2
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human HHATL/GUP1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Hhatl/Gup1 (HHATL Antibody Extrait)
Sujet

GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.

Synonyms: C3orf3, Glycerol uptake/transporter homolog, GUP1, GUP1 glycerol uptake/transporter homolog, Hedgehog acyltransferase like, Hedgehog acyltransferase-like protein, Hhatl, HHATL_HUMAN, KIAA1173, MBOAT3, Membrane bound O acyltransferase domain containing 3, MSTP002, OACT3, Protein-cysteine N-palmitoyltransferase HHAT-like protein.

ID gène 57467
Pathways Signalisation Hedgehog
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months