GNPTAB anticorps (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits) (HRP)

Details for Product anti-GNPTAB Antibody No. ABIN1712364, Fournisseur: Connectez-vous pour afficher
Antigène
  • si:ch211-234f20.3
  • wu:fd55d09
  • zgc:122985
  • zgc:158502
  • GNPTA
  • ICD
  • EG432486
  • mKIAA1208
  • RGD1564821
  • N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
  • GNPTAB
  • gnptab
  • Gnptab
Reactivité
Humain, Souris, Rat (Rattus)
36
31
31
2
2
2
2
2
2
1
1
Hôte
Lapin
36
Clonalité
Polyclonal
Conjugué
Cet anticorp GNPTAB est conjugé à/à la HRP
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
26
10
5
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human N-acetylglucosamine-1-phosphotransferase subunit beta
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gnptab (GNPTAB Antibody Extrait)
Sujet

This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].

Synonyms: N-acetylglucosamine-1-phosphotransferase subunit beta, EC=2.7.8.17, GlcNAc-1-phosphotransferase subunits alpha/beta, GNPTA, GNPTA_HUMAN, Gnptab, KIAA1208, Stealth protein GNPTAB, UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta.

ID gène 79158
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months