Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) anticorps (HRP)

Détails pour le produit réf. ABIN1712365, Fournisseur: Connectez-vous pour afficher
Antigène
  • BEND8
  • BTBD14B
  • BTBD30
  • NAC-1
  • NAC1
  • NACC1
  • 2010001H03Rik
  • 4930511N13Rik
  • Btbd14b
  • Nac1
  • Nac-1
  • EIEE6
  • FEB3
  • FEB3A
  • FHM3
  • GEFSP2
  • HBSCI
  • Nav1.1
  • SCN1
  • SMEI
  • nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
  • sodium channel, voltage-gated, type I, alpha subunit
  • NACC1
  • Nacc1
  • SCN1A
Reactivité
Humain, Souris, Rat (Rattus)
87
44
40
8
6
6
5
4
2
1
1
1
Hôte
Lapin
39
36
16
Clonalité
Polyclonal
Conjugué
HRP
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
68
33
32
28
25
22
15
13
9
1
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from human NAC1/BTBD14B
Isotype IgG
Purification Purified by Protein A.
Autre désignation Nac1/Btbd14b (NACC1 Antibody Extrait)
Sujet

NAC1 is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homooligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.

Synonyms: BEND8, BTB Domain Containing 14B, BTB/POZ domain-containing protein 14B, btbd14b, btbd14b, FLJ37383, NAC-1, NAC1, Nacc1, NACC1_HUMAN, Nucleus accumbens-associated protein 1.

ID gène 112939
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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