PLAG1 anticorps (Pleiomorphic Adenoma Gene 1) (HRP)

Details for Product anti-PLAG1 Antibody No. ABIN1712377, Fournisseur: Connectez-vous pour afficher
Antigène
  • PLAG1
  • MGC152687
  • PSA
  • SGPA
  • ZNF912
  • pleiomorphic adenoma gene 1
  • PLAG1
  • plag1
  • Plag1
Reactivité
Humain, Souris, Rat (Rattus)
65
35
34
4
4
3
3
2
2
1
1
1
1
Hôte
Lapin
59
7
Clonalité
Polyclonal
Conjugué
Cet anticorp PLAG1 est conjugé à/à la HRP
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
40
26
23
5
3
2
1
1
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Immunogène KLH conjugated synthetic peptide derived from human PLAG1
Isotype IgG
Purification Purified by Protein A.
Autre désignation PLAG1 (PLAG1 Antibody Extrait)
Sujet

Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.

Subcellular location: Nucleus

Synonyms: PSA, SGPA, ZNF912, Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1

ID gène 5324
UniProt Q6DJT9
Domaine de recherche Cancer, Transcription Factors
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
Avez-vous cherché autre chose?