PMFBP1 anticorps (Polyamine Modulated Factor 1 Binding Protein 1) (HRP)

Details for Product anti-PMFBP1 Antibody No. ABIN1712379, Fournisseur: Connectez-vous pour afficher
Antigène
  • PMFBP1
  • 1700016D22Rik
  • F77
  • Stap
  • ODF3
  • polyamine modulated factor 1 binding protein 1
  • PMFBP1
  • Pmfbp1
Reactivité
Humain, Souris, Rat (Rattus)
31
19
18
2
2
2
2
2
Hôte
Lapin
24
7
Clonalité
Polyclonal
Conjugué
Cet anticorp PMFBP1 est conjugé à/à la HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
16
13
8
5
4
3
2
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human PMFBP1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Pmfbp1 (PMFBP1 Antibody Extrait)
Sujet

PMF-1 is a 205 amino acid protein involved in kinetochore formation. Localized to the nucleus, PMF-1 contains a coiled-coil domain which interacts with the leucine-zipper domain of Nrf2. This interaction regulates the transcription of SSAT, a regulatory enzyme for polyamine catabolism. PMF-1 is also a component of the MIS12 complex, which is required for kinetochore formation and chromosomal alignment and segregation. PMF-1 is expressed at highest levels in skeletal muscle and heart, with moderate expression in liver and kidney. PMFBP1 (Polyamine-modulated factor 1-binding protein 1) is a 1022 amino acid protein that binds PMF-1 and may be involved in general organization of the cytoskeleton. Due to evidence that PMFBP1 may play a role in sperm tail morphology, it may therefore affect fertility. There are three isoforms of PMFBP1 that are produced as a result of alternative splicing events.

Synonyms: PMF 1 binding protein, PMF-1-binding protein, PMFBP_HUMAN, Pmfbp1, Polyamine modulated factor 1 binding protein 1, Polyamine-modulated factor 1-binding protein 1.

ID gène 83449
Domaine de recherche Stem Cells
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months