ARP1 Actin-Related Protein 1, Centractin (Yeast) (ACTR1) anticorps (HRP)

Détails pour le produit réf. ABIN1712384, Fournisseur: Connectez-vous pour afficher
Antigène
Reactivité
Humain, Souris, Rat (Rattus)
14
14
14
Hôte
Lapin
14
Clonalité
Polyclonal
Conjugué
HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
13
2
2
Options
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Immunogène KLH conjugated synthetic peptide derived from human SKR1/ACTR1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Actr1
Sujet

Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1â€"6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

Subcellular location: Extracellular

Synonyms: Activin Receptor Type IA, Activin A receptor type I, Activin A receptor type II like kinase 2, Activin receptor type I, Activin receptor type-1, Activin receptor-like kinase 2, ACTR1, ACTR 1, ACTR-1, ACTR-I, ACTRI, ACVR 1, ACVR1, ACVR1_HUMAN, ACVR1A, ACVRLK 2, ACVRLK2, ALK 2, ALK-2, ALK2, FOP, Hydroxyalkyl protein kinase, Serine/threonine protein kinase receptor R1, Serine/threonine-protein kinase receptor R1, SKR 1, SKR1, TGF-B superfamily receptor type I, TGFB superfamily receptor type I, TSR-I, TSRI, TSRI.

ID gène 90
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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