Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH . Isoform 2: May have a higher activity than isoform 1.
Subcellular location: Extracellular
Synonyms: KNBC, NBC1, NBC2, pNBC, HNBC1, hhNMC, kNBC1, SLC4A5, NBCe1-A, Electrogenic sodium bicarbonate cotransporter 1, Sodium bicarbonate cotransporter, Na(+)/HCO3(-) cotransporter, Solute carrier family 4 member 4, SLC4A4, NBC, NBCE1