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ANO3 anticorps (Anoctamin 3) (HRP)

Détail du produit anti-ANO3 anticorps No. ABIN1712403, Fournisseur: Connectez-vous pour afficher
Antigène
  • TMEM16C
  • anoctamin-3
  • C11orf25
  • DYT23
  • DYT24
  • AI838058
  • B230324K02Rik
  • Tmem16c
  • anoctamin 3
  • ANO3
  • ano3
  • Ano3
Reactivité
Humain, Souris, Rat (Rattus)
36
27
24
3
3
3
3
2
2
2
1
1
Hôte
Lapin
37
Clonalité
Polyclonal
Conjugué
Cet anticorp ANO3 est conjugé à/à la HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
22
14
13
5
3
2
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human TMEM16C/Anoctamin 3
Isotype IgG
Purification Purified by Protein A.
Autre désignation Tmem16c/Anoctamin 3 (ANO3 Antibody Extrait)
Sujet

TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Subcellular location: Extracellular


Synonyms: ANO3, C11orf25, GENX 3947, TMEM16C, Transmembrane protein 16C eight membrane spanning domains, Transmembrane protein 16C, ANO3_HUMAN.
ID gène 63982
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months