AIP anticorps (Aryl Hydrocarbon Receptor Interacting Protein) (HRP)

Details for Product anti-AIP Antibody No. ABIN1712408, Fournisseur: Connectez-vous pour afficher
Antigène
  • AIP
  • xaip
  • ARA9
  • FKBP16
  • FKBP37
  • SMTPHN
  • XAP-2
  • XAP2
  • wu:fa03h10
  • zgc:101101
  • AA408703
  • AW476050
  • Ara9
  • D19Bwg1412e
  • Fkbp16
  • Xap2
  • aryl hydrocarbon receptor interacting protein
  • aryl-hydrocarbon receptor-interacting protein
  • AIP
  • aip
  • Aip
Reactivité
Humain, Souris, Rat (Rattus)
95
42
38
14
10
10
6
6
4
2
2
1
1
Hôte
Lapin
70
20
10
Clonalité
Polyclonal
Conjugué
Cet anticorp AIP est conjugé à/à la HRP
4
4
3
3
3
3
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
84
43
29
17
11
8
7
4
4
2
2
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human XAP2/ARA9
Isotype IgG
Purification Purified by Protein A.
Autre désignation Xap2/Ara9 (AIP Antibody Extrait)
Sujet

The Aryl hydrocarbon receptor (AhR), also designated dioxin receptor (DR), a ligand-activated transcription factor, becomes activated upon binding of dioxins or structurally related forms of xenobiotics. Upon ligand binding, AhR translocates from the cytoplasm to the nucleus where it complexes with Arnt to form a DNA binding heterodimer. This complex activates transcription of target genes involved in xenobiotic metabolism. Until ligand binding occurs, AhR remains latent in the cytoplasm, which is maintained by its association with the molecular chaperones HSP 90, the hepatitis B virus X-associated protein (XAP2, also designated AIP and ARA9) and the heat shock protein p23. XAP2, a ubiquitously expressed protein, binds to HSP 90 and AhR through a highly conserved carboxy-terminal tetraticopeptide repeat domain. XAP2 participates in stabilizing AhR as well as enhancing the cytoplasmic localization of the receptor. It may also be involved in regulating the degradation of AhR.


Synonyms: AH receptor interacting protein, AH receptor-interacting protein, AIP, AIP, AIP_HUMAN, ARA 9, Aryl hydrocarbon receptor interacting protein, Aryl-hydrocarbon receptor-interacting protein, fa03h10, FKBP 16, FKBP 37, FKBP16, FKBP37, HBV X associated protein 2, HBV X associated protein, HBV X-associated protein 2, HBVX associated protein, Immunophilin homolog ARA 9, Immunophilin homolog ARA9, SMTPHN, XAP 2, XAP-2, XAP2.
ID gène 9049
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months