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ABL1 anticorps (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase) (pThr754) (HRP)

Détail du produit anti-ABL1 anticorps No. ABIN1712438, Fournisseur: Connectez-vous pour afficher
Antigène
  • ABL1
  • ABL
  • CABL
  • ABLL
  • cb272
  • JTK7
  • bcr/abl
  • c-ABL
  • p150
  • v-abl
  • AI325092
  • Abl
  • E430008G22Rik
  • c-Abl
  • MTP
  • c-abl oncogene 1, receptor tyrosine kinase
  • c-abl oncogene 1, non-receptor tyrosine kinase
  • v-abl Abelson murine leukemia viral oncogene homolog 2
  • microsomal triglyceride transfer protein
  • Protein ABL-1
  • ABL1
  • ABL2
  • abl2
  • Abl1
  • MTTP
  • abl-1
Alternatives
anti-Humain ABL1 anticorps pour Immunofluorescence
Épitope
pThr754, pThr735
52
51
42
31
28
28
24
16
16
16
16
15
15
15
15
15
15
15
15
15
11
9
8
8
7
7
6
6
6
6
5
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
603
401
313
10
4
3
1
1
1
1
Hôte
Lapin
601
23
Clonalité
Polyclonal
Conjugué
Cet anticorp ABL1 est conjugé à/à la HRP
31
30
28
16
16
16
15
15
15
15
15
15
15
15
15
15
15
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
355
195
182
158
110
65
43
22
15
11
6
2
2
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform b around the phosphorylation site of Thr754
Isotype IgG
Purification Purified by Protein A.
Autre désignation C-Abl (ABL1 Antibody Extrait)
Sujet

The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9,22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.


Synonyms: c-AblThr754/Thr735, Abelson Murine Leukemia Viral Oncogene Homolog 1, Abelson murine leukemia viral v abl oncogene homolog 1, Abl 1, ABL, Abl protein, Abl1, Bcr/c abl oncogene protein, JTK 7, JTK7, p150, Proto oncogene tyrosine protein kinase ABL1, Transformation gene oncogene ABL, v abl Abelson murine leukemia viral oncogene homolog 1, v abl, ABL1_HUMAN.
ID gène 25
Pathways Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months