FGFR1 anticorps (Fibroblast Growth Factor Receptor 1) (pTyr154) (HRP)

Details for Product anti-FGFR1 Antibody No. ABIN1712440, Fournisseur: Connectez-vous pour afficher
Antigène
  • FGFR
  • fgfr
  • X1FGFR
  • XFGFR-1
  • XFGFRA2
  • bfgfr
  • cek
  • fgfr1
  • flg
  • flt-2
  • flt2
  • kal2
  • ogd
  • xfgfr1
  • CG7223
  • CT22273
  • CT39172
  • DFGF-R1
  • DFGF-R2
  • DFR-1
  • DFR1
  • DFR1/DFGF-R2
  • DPR3
  • DTRK(FR1)
  • Dfr-1
  • Dfr1
  • DmHD-38
  • Dmel\\CG7223
  • Dtk1
  • EMS2
  • FGF-R2
  • FGFR2
  • FR1
  • Fr1
  • HD-38
  • HTL/FGFR1
  • Htl
  • Tk1
  • dtk1
  • i100
  • i150
  • i79
  • j372
  • cd331
  • fgfbr
  • fgfr-1
  • hbgfr
  • n-sam
  • ach
  • cd333
  • cek2
  • fgfr-3
  • hsfgfr3ex
  • jtk4
  • BFGFR
  • CD331
  • CEK
  • FGFBR
  • FGFR-1
  • FLG
  • FLT-2
  • FLT2
  • HBGFR
  • HH2
  • KAL2
  • N-SAM
  • OGD
  • bFGF-R-1
  • AW208770
  • Eask
  • Fgfr-1
  • Flt-2
  • Hspy
  • FLG-1
  • FGFRI
  • x1fgfr
  • cb231
  • sb:cb231
  • fibroblast growth factor receptor
  • fibroblast growth factor receptor 1
  • basic fibroblast growth factor receptor 1
  • heartless
  • fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)
  • Fibroblast growth factor receptor 1
  • fibroblast growth factor receptor 1a
  • FGFR
  • fgfr
  • fgfr1-a
  • CpipJ_CPIJ005849
  • htl
  • fgfr1
  • fgfr3
  • FGFR1
  • Fgfr1
  • fgfr1-b
  • fgfr1a
Épitope
pTyr154
62
59
56
53
40
37
36
36
34
14
12
12
12
11
11
10
10
10
10
9
9
9
8
8
8
6
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
625
284
221
21
14
14
11
11
7
6
4
4
2
2
2
1
1
Hôte
Lapin
422
179
35
Clonalité
Polyclonal
Conjugué
Cet anticorp FGFR1 est conjugé à/à la HRP
34
31
27
23
19
19
9
9
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
526
241
169
110
94
77
66
52
48
22
18
10
8
4
2
1
1
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Immunogène KLH conjugated synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyr154
Isotype IgG
Purification Purified by Protein A.
Autre désignation Fgfr1 (FGFR1 Antibody Extrait)
Sujet

Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.

Synonyms: FGFR1 phospho Y154, FGFR1 phospho Tyr154, p-FGFR1 phospho Y154, bFGF R, BFGFR, C FGR, CD 331, CD331, CD331 antigen, CEK, FGFBR, FGFR 1, Fibroblast growth factor receptor 1, FLG, FLG protein, FLJ14326, FLT 2, FLT2, Fms like tyrosine kinase 2, Fms related tyrosine kinase 2, Fms related tyrosine kinase 2 Pfefer syndrome, H2, H3, H4, H5, HBGFR, Heparin binding growth factor receptor, Hydroxyaryl protein kinase, KAL 2, KAL2, MFR, N SAM, N sam tyrosine kinase, Protein tyrosine kinase, Tyrosylprotein kinase, Basic fibroblast growth factor receptor 1, FGFR1_HUMAN.

ID gène 2260
Domaine de recherche Cancer, Growth Factors, Tyrosine Kinases, Angiogenesis, Cytokines, Receptors
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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