FGFR1 anticorps (pTyr154) (HRP)

N° du produit ABIN1712440

Détail du produit anti-FGFR1 anticorps (HRP)

Antigène: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Épitope: pTyr154

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR1 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyr154

Isotype: IgG

Information d'application

Indications d'application: IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FGFR1

Antigène: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Autre désignation: FGFR1 (FGFR1 Produits)

Synonymes: anticorps FGFR, anticorps fgfr, anticorps X1FGFR, anticorps XFGFR-1, anticorps XFGFRA2, anticorps bfgfr, anticorps cek, anticorps fgfr1, anticorps flg, anticorps flt-2, anticorps flt2, anticorps kal2, anticorps ogd, anticorps xfgfr1, anticorps CG7223, anticorps CT22273, anticorps CT39172, anticorps DFGF-R1, anticorps DFGF-R2, anticorps DFR-1, anticorps DFR1, anticorps DFR1/DFGF-R2, anticorps DPR3, anticorps DTRK(FR1), anticorps Dfr-1, anticorps Dfr1, anticorps DmHD-38, anticorps Dmel\\CG7223, anticorps Dtk1, anticorps EMS2, anticorps FGF-R2, anticorps FGFR2, anticorps FR1, anticorps Fr1, anticorps HD-38, anticorps HTL/FGFR1, anticorps Htl, anticorps Tk1, anticorps dtk1, anticorps i100, anticorps i150, anticorps i79, anticorps j372, anticorps cd331, anticorps fgfbr, anticorps fgfr-1, anticorps hbgfr, anticorps n-sam, anticorps ach, anticorps cd333, anticorps cek2, anticorps fgfr-3, anticorps hsfgfr3ex, anticorps jtk4, anticorps BFGFR, anticorps CD331, anticorps CEK, anticorps FGFBR, anticorps FGFR-1, anticorps FLG, anticorps FLT-2, anticorps FLT2, anticorps HBGFR, anticorps HH2, anticorps KAL2, anticorps N-SAM, anticorps OGD, anticorps bFGF-R-1, anticorps AW208770, anticorps Eask, anticorps Fgfr-1, anticorps Flt-2, anticorps Hspy, anticorps FLG-1, anticorps FGFRI, anticorps x1fgfr, anticorps cb231, anticorps sb:cb231, anticorps fibroblast growth factor receptor, anticorps fibroblast growth factor receptor 1 S homeolog, anticorps basic fibroblast growth factor receptor 1, anticorps heartless, anticorps fibroblast growth factor receptor 1, anticorps fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog, anticorps Fibroblast growth factor receptor 1, anticorps fibroblast growth factor receptor 1 L homeolog, anticorps fibroblast growth factor receptor 1a, anticorps FGFR, anticorps fgfr, anticorps fgfr1.S, anticorps CpipJ_CPIJ005849, anticorps htl, anticorps fgfr1, anticorps fgfr3.L, anticorps FGFR1, anticorps Fgfr1, anticorps fgfr1.L, anticorps fgfr1a

Sujet:

Synonyms: FGFR1 phospho Y154, FGFR1 phospho Tyr154, p-FGFR1 phospho Y154, bFGF R, BFGFR, C FGR, CD 331, CD331, CD331 antigen, CEK, FGFBR, FGFR 1, Fibroblast growth factor receptor 1, FLG, FLG protein, FLJ14326, FLT 2, FLT2, Fms like tyrosine kinase 2, Fms related tyrosine kinase 2, Fms related tyrosine kinase 2 Pfefer syndrome, H2, H3, H4, H5, HBGFR, Heparin binding growth factor receptor, Hydroxyaryl protein kinase, KAL 2, KAL2, MFR, N SAM, N sam tyrosine kinase, Protein tyrosine kinase, Tyrosylprotein kinase, Basic fibroblast growth factor receptor 1, FGFR1_HUMAN.

Background: Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.

ID gène: 2260

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins