Aconitase 1 anticorps (ACO1) (pSer138) (HRP)

Details for Product anti-ACO1 Antibody No. ABIN1712476, Fournisseur: Connectez-vous pour afficher
Antigène
  • AI256519
  • Aco-1
  • Irebp
  • Irp1
  • aconitase 1
  • Aco1
Épitope
pSer138
17
14
2
2
2
2
2
2
2
2
2
Reactivité
Humain, Souris, Rat (Rattus)
74
57
50
3
2
2
1
1
Hôte
Lapin
70
10
Clonalité
Polyclonal
Conjugué
Cet anticorp Aconitase 1 est conjugé à/à la HRP
6
4
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
40
39
21
11
10
10
7
7
4
1
Options
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic phosphopeptide derived from human Aconitase 1 around the phosphorylation site of Ser138 [AD(p-S)LQ]
Isotype IgG
Purification Purified by Protein A.
Autre désignation Aconitase 1 (ACO1 Antibody Extrait)
Sujet

Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins, iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IREâ€"BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.

Synonyms: Aconitase 1 phospho S138, p-Aconitase 1 phospho S138, ACO 1, ACO1, ACOC_HUMAN, Aconitase 1 soluble, Aconitase, Aconitase1, Aconitate hydratase, ACONS, Citrate hydro lyase, Citrate hydro-lyase, Cytoplasmic aconitate hydratase, Ferritin repressor protein, IRE BP 1, IRE-BP 1, IREB 1, IREB1, IREBP, IREBP1, Iron regulatory protein 1, Iron responsive element binding protein 1, Iron-responsive element-binding protein 1, IRP 1, IRP1, OTTHUMP00000045233.

ID gène 48
Domaine de recherche Signaling, Metabolism, DNA/RNA
Pathways Transition Metal Ion Homeostasis
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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