Deleted In Azoospermia 4 (DAZ4) anticorps (HRP)

Détails pour le produit réf. ABIN1712511, Fournisseur: Connectez-vous pour afficher
Antigène
  • DAZ2
  • DAZ3
  • DAZ4
  • pDP1680
  • pDP1681
  • deleted in azoospermia 2
  • deleted in azoospermia 3
  • deleted in azoospermia 4
  • DAZ2
  • DAZ3
  • DAZ4
Reactivité
Humain, Souris, Rat (Rattus)
50
18
18
4
3
3
2
2
2
2
Hôte
Lapin
49
1
Clonalité
Polyclonal
Conjugué
HRP
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
36
21
17
13
10
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human DAZ4
Isotype IgG
Purification Purified by Protein A.
Autre désignation Daz4 (DAZ4 Antibody Extrait)
Sujet

Spermatogenesis is the process by which male spermatogonia develop into mature spermatozoa. DAZ (deleted in azoospermia) are RNA-binding proteins that play an essential role in spermatogenesis. DAZ proteins influence the first stages of spermatogenesis and the maintenance of germ cell populations. DAZ proteins (DAZ1, DAZ2, DAZ3, DAZ4 and DAZ5) are encoded by separate genes on chromosome Y, each of which contain an AZFc domain in their coding region. DAZ proteins localize to the nucleus of spermatogonia, but relocate to the cytoplasm during meiosis. DAZ proteins contain an RRM (RNA recognition motif) domain that may regulate mRNA translation by binding to the 3’UTR. Deletions in the genes encoding DAZ proteins may cause azoospermia or oligospermia which can lead to male infertility. DAZ4 (deleted in azoospermia 4), also known as pDP1680 or pDP1681, is a 579 amino acid testis specific protein that contains nine DAZ-like domains and two RNA recognition motifs (RRM). DAZ4 exists as two alternatively spliced isoforms.

Synonyms: DAZ4, Deleted in azoospermia 4, Deleted in azoospermia protein 4.

Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months