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Ggt5 Light Chain (Light Chain) anticorps (HRP)

Détails pour le produit réf. ABIN1712530, Fournisseur: Connectez-vous pour afficher
Antigène
Épitope
Light Chain
14
Reactivité
Humain, Souris, Rat (Rattus)
14
14
14
Hôte
Lapin
14
Clonalité
Polyclonal
Conjugué
HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
13
12
2
2
Options
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Immunogène KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 5 light chain
Isotype IgG
Purification Purified by Protein A.
Sujet

g-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors. This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion. In humans, hepatic GGT activity is elevated in some liver diseases. GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma. GGT5 converts Leukotriene C4 to Leukotriene D4, it does not, however, convert synthetic substrates that are commonly used to assay GGT. In human serum and tissues there is a marked heterogeneity in GGT, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes.

Subcellular location: Extracellular


Synonyms: Gamma glutamyl transpeptidase related enzyme, Gamma glutamyltranspeptidase 5, Gamma-glutamyl transpeptidase-related enzyme, Gamma-glutamyltransferase 5 heavy chain, Gamma-glutamyltransferase-like activity 1, Gamma-glutamyltranspeptidase 5, GGT 5, GGT REL, GGT-rel, GGT5, GGT5_HUMAN, DKFZP566O011, GGTLA1, Glutathione hydrolase 5, Leukotriene-C4 hydrolase, Gamma-glutamyltransferase 5 light chain.
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months