GGA3 anticorps (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3) (HRP)

Details for Product anti-GGA3 Antibody No. ABIN1712535, Fournisseur: Connectez-vous pour afficher
Antigène
  • C230037M19Rik
  • mKIAA0154
  • golgi associated, gamma adaptin ear containing, ARF binding protein 3
  • golgi-associated, gamma adaptin ear containing, ARF binding protein 3
  • Gga3
  • GGA3
Reactivité
Humain, Souris, Rat (Rattus)
61
27
26
7
4
3
2
2
2
2
2
2
2
2
1
1
1
Hôte
Lapin
36
20
3
3
Clonalité
Polyclonal
Conjugué
Cet anticorp GGA3 est conjugé à/à la HRP
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
33
26
13
12
10
9
3
2
2
Options
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Immunogène KLH conjugated synthetic peptide derived from human GGA3
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gga3 (GGA3 Antibody Extrait)
Sujet

The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46 % sequence identity with GGA1 and 38 % with GGA2.

Synonyms: ADP ribosylation factor binding protein 3, ADP ribosylation factor binding protein GGA 3, ADP ribosylation factor binding protein GGA3, ADP-ribosylation factor-binding protein GGA3, ARF binding protein GGA 3, ARF binding protein GGA3, ARF-binding protein 3, gamma ear-containing, GGA 3, GGA3, GGA3_HUMAN, Golgi associated gamma adaptin ear containing ARF binding protein 3, Golgi localized gamma ear containing ARF binding protein 3, Golgi-localized, KIAA0154.

ID gène 23163
Domaine de recherche Signaling
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months