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Protein Kinase C Substrate 80K-H (PRKCSH) anticorps (HRP)

Détails pour le produit réf. ABIN1712538, Fournisseur: Connectez-vous pour afficher
Antigène
  • zgc:55653
  • prkcsh
  • MGC75615
  • MGC82696
  • PRKCSH
  • MCD7.9
  • MCD7_9
  • PRIORITY IN SWEET LIFE 4
  • PLD1
  • AGE-R2
  • G19P1
  • PCLD
  • PKCSH
  • 80K-H
  • VASAP-60
  • protein kinase C substrate 80K-H
  • glucosidase II beta subunit protein PSL4
  • phospholipase D1, phosphatidylcholine-specific
  • prkcsh
  • PRKCSH
  • PSL4
  • Bm1_42055
  • LOC100304710
  • PLD1
  • LOC100526729
  • Prkcsh
Alternatives
anti-Humain Protein Kinase C Substrate 80K-H anticorps pour Immunocytochemistry
Reactivité
Humain, Souris, Rat (Rattus)
87
29
21
3
2
2
2
2
2
1
Hôte
Lapin
81
6
Clonalité
Polyclonal
Conjugué
HRP
6
6
5
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
64
37
22
14
13
10
7
2
1
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human Glucosidase 2 subunit beta
Isotype IgG
Purification Purified by Protein A.
Autre désignation Glucosidase 2 Subunit beta (PRKCSH Antibody Extrait)
Sujet

Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER). Glucosidase II is an ER-localized enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb) which form a defined heterodimeric complex. Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit. The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C-terminus. The phosphorylated form of Glucosidase IIb is localized in the plasma membrane and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma cells. Glucosidase IIb was first purified from a human carcinoma cell line as a potential substrate for protein kinase C. Through the HDEL signal at the C-terminus, Glucosidase IIb retains the complete complex in the ER.


Synonyms: 80K-H protein, AGE-binding receptor 2, AGE-R2, G19P1, GLU2B_HUMAN, Glucosidase 2 subunit beta, Glucosidase II beta subunit, Glucosidase II subunit beta, Hepatocystin, PCLD, PKCSH, PLD1, PRKCSH, Protein kinase C substrate 60.1 kDa protein heavy chain, Protein kinase C substrate 80 Kda protein, Protein kinase C substrate 80K-H, Protein kinase C substrate, 80 Kda protein.
ID gène 5589
Pathways Cellular Glucan Metabolic Process, Methionine Biosynthetic Process
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months