GNPDA1 anticorps (AA 201-289) (HRP)

N° du produit ABIN1712543

Détail du produit anti-GNPDA1 anticorps (HRP)

Antigène: GNPDA1 (Glucosamine-6-Phosphate Deaminase 1 (GNPDA1))

Épitope: AA 201-289

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNPDA1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GNPDA1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GNPDA1

Antigène: GNPDA1 (Glucosamine-6-Phosphate Deaminase 1 (GNPDA1))

Autre désignation: GNPDA1 (GNPDA1 Produits)

Synonymes: anticorps GNP1, anticorps GNPDA, anticorps GNPI, anticorps GPI, anticorps HLN, anticorps Gnp1, anticorps Gnpi, anticorps oscillin, anticorps gnpda, anticorps gnpi, anticorps gpi, anticorps hln, anticorps GNPDA1, anticorps zgc:110691, anticorps glucosamine-6-phosphate deaminase 1, anticorps glucosamine-6-phosphate deaminase 1 S homeolog, anticorps Glucosamine-6-phosphate deaminase 1, anticorps GNPDA1, anticorps Gnpda1, anticorps gnpda1.S, anticorps gnpda1, anticorps MSMEG_0501, anticorps nagB, anticorps PPSC2_c4268

Sujet:

Synonyms: EC 3.5.99.6, GlcN6P deaminase 1, Glucosamine 6 phosphate deaminase 1, Glucosamine 6 phosphate isomerase 1, Glucosamine-6-phosphate deaminase 1, Glucosamine-6-phosphate isomerase 1, GNPDA 1, GNPDA1, GNPI, GNPI1_HUMAN, HLN, KIAA0060, Oscillin, Putative glucosamine 6 phosphate isomerase.

Background: During fertilization in mammals, the sperm activates the egg by causing an increase in the level of free cytoplasmic calcium concentration. This increased calcium concentration induces a characteristic series of oscillations that trigger egg activation and early embryo development. A hamster protein named oscillin is thought to be involved in this pathway. The enzyme glucosamine-6-phosphate isomerase (GNPI) or deaminase (GNPDA1) and the related protein GNPDA2 are the human homologs of hamster oscillin. GNPDA1 and GNPDA2 catalyze the conversion of GNP to fructose-6-phosphate and ammonia. Both proteins exist as homohexamers and are ubiquitously expressed with highest expression in testis, ovary and heart. Three isoforms of GNPDA2 are expressed due to alternative splicing events.

ID gène: 10007