DNAJB2 anticorps (AA 21-120) (HRP)

N° du produit ABIN1712555

Détail du produit anti-DNAJB2 anticorps (HRP)

Antigène: DNAJB2 (DnaJ (Hsp40) Homolog, Subfamily B, Member 2 (DNAJB2))

Épitope: AA 21-120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJB2 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSJ1/DNAJB2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DNAJB2

Antigène: DNAJB2 (DnaJ (Hsp40) Homolog, Subfamily B, Member 2 (DNAJB2))

Autre désignation: HSJ1 (DNAJB2 Produits)

Synonymes: anticorps MGC78895, anticorps DSMA5, anticorps HSJ-1, anticorps HSJ1, anticorps HSPF3, anticorps 2700059H22Rik, anticorps Dnajb10, anticorps Hsj1, anticorps mDj8, anticorps DnaJ heat shock protein family (Hsp40) member B2 L homeolog, anticorps DnaJ heat shock protein family (Hsp40) member B2, anticorps dnajb2.L, anticorps DNAJB2, anticorps dnajb2, anticorps Dnajb2

Sujet:

Synonyms: Descriptions, DnaJ Hsp40 homolog subfamily B member 2, DnaJ homolog subfamily B member 2, DnaJ protein homolog 1, DNAJB2, Heat shock 40 kDa protein 3, Heat shock protein J1, Heat shock protein neuronal DNAJ like 1, HSJ 1, HSJ1, HSPF3, DNJB2_HUMAN.

Background: The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. Two isoforms are produced due to alternative splicing.

ID gène: 3300