DnaJ (Hsp40) Homolog, Subfamily B, Member 2 (DNAJB2) anticorps (HRP)

Détails pour le produit réf. ABIN1712555, Fournisseur: Connectez-vous pour afficher
Antigène
  • MGC78895
  • DSMA5
  • HSJ-1
  • HSJ1
  • HSPF3
  • 2700059H22Rik
  • Dnajb10
  • Hsj1
  • mDj8
  • DnaJ (Hsp40) homolog, subfamily B, member 2
  • dnajb2
  • DNAJB2
  • Dnajb2
Reactivité
Humain, Souris, Rat (Rattus)
86
23
21
3
Hôte
Lapin
63
23
Clonalité
Polyclonal
Conjugué
HRP
5
5
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
67
34
13
9
9
8
4
3
2
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human HSJ1/DNAJB2
Isotype IgG
Purification Purified by Protein A.
Autre désignation Hsj1 (DNAJB2 Antibody Extrait)
Sujet

The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. Two isoforms are produced due to alternative splicing.

Synonyms: Descriptions, DnaJ Hsp40 homolog subfamily B member 2, DnaJ homolog subfamily B member 2, DnaJ protein homolog 1, DNAJB2, Heat shock 40 kDa protein 3, Heat shock protein J1, Heat shock protein neuronal DNAJ like 1, HSJ 1, HSJ1, HSPF3, DNJB2_HUMAN.

ID gène 3300
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months