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MIXL1 anticorps (Mix Paired-Like Homeobox) (HRP)

Détail du produit anti-MIXL1 anticorps No. ABIN1712560, Fournisseur: Connectez-vous pour afficher
Antigène
  • MIXL1
  • MILD1
  • MIX
  • MIXL
  • CMIX
  • Mm1
  • Mml
  • Mix1 homeobox-like 1 (Xenopus laevis)
  • Mix-like homeobox protein 1
  • Mix paired-like homeobox
  • Mix paired-like homeobox 1
  • MIXL1
  • LOC100347077
  • Mixl1
Reactivité
Humain, Souris, Rat (Rattus)
34
31
14
1
Hôte
Lapin
39
3
Clonalité
Polyclonal
Conjugué
Cet anticorp MIXL1 est conjugé à/à la HRP
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
28
19
13
2
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human MIXL1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Mixl1 (MIXL1 Antibody Extrait)
Sujet

The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and in the control of gene expression. MIXL1 (Mix1 homeobox-like 1), also known as MIXL, is a 232 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in lymph tissues, MIXL1 functions as a transcription factor that plays an essential role in axial mesendoderm morphogenesis and endoderm formation and is also required for cellular differentiation during blood development. Additionally, MIXL1 is involved in maturation of heart and gut tissue during embryogenesis and may also act as a negative regulator of brachyury expression. Overexpression of MIXL1 is associated with non-Hodgkin and Hodgkin lymphomas, suggesting a role in carcinogenesis.


Synonyms: hMix, Homeobox protein MIXL1, Homeodomain protein 1, Homeodomain protein MIX, MILD1, MIX, Mix.1, Mix.1 homeobox-like protein, Mix1 homeobox-like 1, MIX1 homeobox-like protein 1, Mixl1, MIXL1_HUMAN.
ID gène 83881
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months