FOXL2 anticorps (Forkhead Box L2) (pSer263) (HRP)

Details for Product anti-FOXL2 Antibody No. ABIN1712580, Fournisseur: Connectez-vous pour afficher
Antigène
  • FOXL2
  • zgc:136549
  • foxl2
  • FoxL2
  • foxL2
  • AU045128
  • BPES
  • PINTO
  • Pfrk
  • BPES1
  • PFRK
  • POF3
  • forkhead box L2
  • FoxL protein
  • forkhead transcription factor L2
  • foxl2 protein
  • fork-head box L2 transcription factor
  • FOXL2
  • foxl2
  • Foxl2
  • foxL
  • FoxL2
  • foxL2
Alternatives
anti-Humain FOXL2 anticorps pour Immunohistochemistry (Whole Mount)
Épitope
pSer263
21
19
19
9
9
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
94
42
35
10
8
7
5
5
3
2
2
1
Hôte
Lapin
74
17
6
Clonalité
Polyclonal
Conjugué
Cet anticorp FOXL2 est conjugé à/à la HRP
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
75
37
18
13
10
7
5
4
4
3
3
2
2
1
Options
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Immunogène KLH conjugated synthetic phosphopeptide derived from human FOXL2 around the phosphorylation site of Ser263
Isotype IgG
Purification Purified by Protein A.
Autre désignation Foxl2 (FOXL2 Antibody Extrait)
Sujet

Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

Synonyms: FOXL2 phospho S263, p-FOXL2 phospho S263, blepharophimosis, Blepharophimosis epicanthus inversus and ptosis 1, Blepharophimosis epicanthus inversus and ptosis, BPES 1, BPES, BPES1, epicanthus inversus and ptosis 1, forkhead box L2, Forkhead box protein L2, forkhead transcription factor FOXL2, FOX L2, FOXL 2, FOXL2, FOXL2_HUMAN, PFRK, PINTO, POF 3, POF3.

ID gène 668
Domaine de recherche Chromatin and Nuclear Signaling, Transcription Factors
Pathways Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months