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GATA2 anticorps (GATA Binding Protein 2) (pSer401) (HRP)

Détail du produit anti-GATA2 anticorps No. ABIN1712589, Fournisseur: Connectez-vous pour afficher
Antigène
  • GATA2
  • Gata2
  • DCML
  • MONOMAC
  • NFE1B
  • xgata-2
  • xgata2
  • GATA-2
  • NF-E1b
  • Gata-2
  • GATA binding protein 2
  • amidase
  • glutamyl/aspartyl-tRNA(Gln/Asp) amidotransferasesubunit A
  • hypothetical protein
  • glutamyl-tRNA(Gln) amidotransferase, subunit GatA (Glu-ADT subunit A)
  • GATA2 transcription factor
  • endothelial transcription factor GATA-2
  • uterine GATA-4 transcription factor
  • GATA2
  • LOC100222005
  • gatA2
  • Gata2
  • Smp_018590
  • gata2
  • LOC100008832
Alternatives
anti-Humain GATA2 anticorps pour Immunohistochemistry (Paraffin-embedded Sections)
Épitope
pSer401
26
12
10
10
7
5
5
5
5
3
3
3
2
2
2
2
1
1
1
1
1
1
Reactivité
Humain
121
31
19
4
3
3
3
3
3
2
2
2
1
1
Hôte
Lapin
92
28
3
Clonalité
Polyclonal
Conjugué
Cet anticorp GATA2 est conjugé à/à la HRP
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
98
46
28
24
18
13
12
11
4
3
3
2
2
2
2
Options
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Immunogène KLH conjugated synthetic phosphopeptide derived from human GATA2 around the phosphorylation site of Ser401
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gata2 (GATA2 Antibody Extrait)
Sujet

Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.


Synonyms: GATA2 phospho S401, p-GATA2 phospho S401, GATA-2, GATA 2, GATA Binding Protein 2, GATA-binding protein 2, Gata2, GATA2_HUMAN, MGC2306, NFE 1B, NFE1B.
ID gène 2624
Domaine de recherche Cardiogenesis, Lineage Markers, Transcription Factors
Pathways Stem Cell Maintenance
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months