SKAP1 anticorps (Src Kinase Associated phosphoprotein 1) (HRP)

Details for Product anti-SKAP1 Antibody No. ABIN1712604, Fournisseur: Connectez-vous pour afficher
Antigène
  • 1700091G21Rik
  • Scap1
  • Skap-55
  • SCAP1
  • SKAP55
  • Skap55
  • src family associated phosphoprotein 1
  • src kinase associated phosphoprotein 1
  • Skap1
  • SKAP1
Reactivité
Humain, Rat (Rattus)
78
25
8
3
1
1
1
Hôte
Lapin
64
15
1
Clonalité
Polyclonal
Conjugué
Cet anticorp SKAP1 est conjugé à/à la HRP
7
7
6
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
55
35
14
13
11
4
4
2
Options
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Immunogène KLH conjugated synthetic peptide derived from human SKAP55
Isotype IgG
Purification Purified by Protein A.
Autre désignation Skap55 (SKAP1 Antibody Extrait)
Sujet

Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines. SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.

Synonyms: pp55, SCAP 1, SCAP1, SKAP 1, SKAP 55, SKAP-55, Skap1, SKAP1_HUMAN, SKAP55 adaptor protein, SRC family associated phosphoprotein 1, Src family-associated phosphoprotein 1, Src kinase associated phosphoprotein 1, SRC kinase associated phosphoprotein 55 kD, Src kinase associated phosphoprotein of 55 kDa, Src kinase-associated phosphoprotein 1, Src kinase-associated phosphoprotein of 55 kDa.

Domaine de recherche Signaling, Tyrosine Kinases
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months