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beta-Amyloid (AA 1-42) anticorps (HRP)

Détails pour le produit réf. ABIN1712606, Fournisseur: Connectez-vous pour afficher
Antigène
Épitope
AA 1-42
14
9
7
3
2
2
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Rat (Rattus)
55
23
12
Hôte
Souris
34
22
Clonalité
Polyclonal
Conjugué
HRP
3
3
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
37
34
20
10
8
8
3
2
2
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from human beta-Amyloid (1-42)
Isotype IgG
Purification Purified by Protein A.
Sujet

The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.

Subcellular location: Extracellular


Synonyms: beta-Amyloid1-42, A4, AAA, ABETA, ABPP, AD1, Alzheimers Disease Amyloid Protein, Amyloid B, Amyloid Beta A4 Protein Precursor, Amyloid Beta, Amyloid of Aging and Alzheimer Disease, APP, APPI, B Amyloid, Beta APP, Cerebral Vascular Amyloid Peptide, CTFgamma, CVAP, PN II, PN2, PreA4, Protease nexin II, A beta, Amyloid 1-42.
ID gène 351
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months