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C5AR1 anticorps (Complement Component 5a Receptor 1) (AA 95-110) (HRP)

Détail du produit anti-C5AR1 anticorps No. ABIN1712609, Fournisseur: Connectez-vous pour afficher
Antigène
  • C5AR1
  • C5R1
  • GPR77
  • C5aR
  • C5r1
  • Cd88
  • D7Msu1
  • C5A
  • C5AR
  • CD88
  • complement component 5a receptor 1
  • C5a anaphylatoxin chemotactic receptor-like
  • C5AR1
  • c5ar1
  • LOC100352978
  • C5ar1
Épitope
AA 95-110
27
20
15
14
13
9
8
6
6
5
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Humain
172
83
28
20
16
11
4
4
2
2
1
1
1
1
1
1
1
1
Hôte
Lapin
106
77
76
1
Clonalité
Polyclonal
Conjugué
Cet anticorp C5AR1 est conjugé à/à la HRP
29
12
11
9
6
5
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
184
94
46
46
41
28
22
13
11
11
5
3
3
3
2
2
2
2
1
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from human C5R1
Isotype IgG
Purification Purified by Protein A.
Autre désignation C5R1 (C5AR1 Antibody Extrait)
Sujet

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).

Subcellular location: Extracellular, Secreted


Synonyms: C5A, C5AR, C5R1, CD88, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5AR1
ID gène 728
UniProt P21730
Domaine de recherche Signaling, Metabolism, Innate Immunity
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months