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GBA3 anticorps (Glucosidase, Beta, Acid 3 (Cytosolic)) (HRP)

Détail du produit anti-GBA3 anticorps No. ABIN1712610, Fournisseur: Connectez-vous pour afficher
Antigène
  • im:6912508
  • CBG
  • CBGL1
  • GLUC
  • KLRP
  • glucosidase, beta, acid 3
  • zgc:112375
  • glucosidase, beta, acid 3 (cytosolic)
  • cytosolic beta-glucosidase
  • Gba3
  • zgc:112375
  • GBA3
  • LOC100344458
Reactivité
Humain, Rat (Rattus)
97
16
2
2
1
1
1
1
1
1
Hôte
Lapin
60
37
Clonalité
Polyclonal
Conjugué
Cet anticorp GBA3 est conjugé à/à la HRP
5
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
68
35
27
21
13
10
5
3
3
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human GBA3/CBG
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gba3/Cbg (GBA3 Antibody Extrait)
Sujet

CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher’s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.


Synonyms: CBG, CBGL1, Cytosolic beta glucosidase, Cytosolic beta glucosidase like protein 1, Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1, GBA3, GBA3_HUMAN, GLUC, Glucosidase beta acid 3, Klotho related protein.
ID gène 57733
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months