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CMKLR1 anticorps (AA 151-250) (HRP)

CMKLR1 Reactivité: Humain, Souris, Rat, Porc WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712633
  • Antigène Voir toutes CMKLR1 Anticorps
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    Épitope
    • 15
    • 15
    • 14
    • 11
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivité
    • 68
    • 41
    • 23
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Porc
    Hôte
    • 70
    • 3
    • 2
    Lapin
    Clonalité
    • 68
    • 6
    • 1
    Polyclonal
    Conjugué
    • 32
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CMKLR1 est conjugé à/à la HRP
    Application
    • 61
    • 28
    • 26
    • 26
    • 20
    • 12
    • 9
    • 9
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Porc, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from mouse CMKLR1
    Isotype
    IgG
    Top Product
    Discover our top product CMKLR1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    Autre désignation
    CMKLR1 (CMKLR1 Produits)
    Synonymes
    anticorps CHEMERINR, anticorps ChemR23, anticorps DEZ, anticorps RVER1, anticorps Gpcr27, anticorps mcmklr1, anticorps si:ch211-240b21.3, anticorps CMLKR1, anticorps Cmklr-1, anticorps GPCR, anticorps chemerin chemokine-like receptor 1, anticorps chemokine-like receptor 1, anticorps CMKLR1, anticorps Cmklr1, anticorps cmklr1
    Sujet

    Synonyms: DEZ, Gpcr27, ChemR23, mcmklr1, Chemokine-like receptor 1, G-protein coupled receptor DEZ, Cmklr1

    Background: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B (By similarity). Positively regulates adipogenesis and adipocyte metabolism.

    ID gène
    14747
    UniProt
    P97468
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