PRKAA1 anticorps (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit) (pSer356) (HRP)

Details for Product anti-PRKAA1 Antibody No. ABIN1712642, Fournisseur: Connectez-vous pour afficher
Antigène
  • Prkaa1
  • ampk
  • ampka1
  • PRKAA1
  • AMPK
  • AMPKa1
  • AMPKalpha1
  • AI194361
  • AI450832
  • AL024255
  • C130083N04Rik
  • cb116
  • im:7154392
  • sb:cb130
  • wu:fa94c10
  • AMPK1
  • protein kinase, AMP-activated, alpha 3 catalytic subunit
  • protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Prkaa3
  • PRKAA1
  • prkaa1
  • Prkaa1
Alternatives
anti-Rat (Rattus) PRKAA1 anticorps pour ELISA
Épitope
pSer356
30
23
18
16
16
14
12
10
8
5
5
5
4
4
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Souris, Rat (Rattus)
301
195
185
28
19
17
10
9
9
8
6
5
5
4
3
3
2
2
1
1
Hôte
Lapin
251
65
1
Clonalité
Polyclonal
Conjugué
Cet anticorp PRKAA1 est conjugé à/à la HRP
12
11
11
8
7
7
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
260
115
103
93
70
38
29
26
21
5
4
3
2
2
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic phosphopeptide derived from mouse AMPK alpha 1 around the phosphorylation site of Ser356
Isotype IgG
Purification Purified by Protein A.
Autre désignation Ampk alpha 1 (PRKAA1 Antibody Extrait)
Sujet

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]

Subcellular location: Cytoplasm, Nucleus


Synonyms: 5'-AMP-activated protein kinase catalytic subunit alpha-1, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1, PRKAA1, AMPK1.
ID gène 5562
Domaine de recherche Cancer, Fatty Acids, Alzheimer's Disease
Pathways AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months