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Chloride Channel Accessory 3, Pseudogene (CLCA3P) anticorps (HRP)

Détails pour le produit réf. ABIN1712645, Fournisseur: Connectez-vous pour afficher
Antigène
  • Clca3
  • CLCA3
  • Clca1
  • Clca2
  • gob-5
  • gob5
  • chloride channel accessory 1
  • chloride channel accessory 3, pseudogene
  • chloride channel calcium activated 3
  • Clca1
  • CLCA3P
  • Clca3
Reactivité
Souris, Rat (Rattus)
14
14
9
Hôte
Lapin
23
Clonalité
Polyclonal
Conjugué
HRP
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
13
10
7
2
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Immunogène KLH conjugated synthetic peptide derived from mouse CLCA3
Isotype IgG
Purification Purified by Protein A.
Autre désignation Clca3 (CLCA3P Antibody Extrait)
Sujet

The calcium-activated chloride channel (CLCA) protein family, which includes the human homologs CLCA1 and CLCA2, display distinct tissue distribution patterns. CLCA1 is expressed as a precursor protein that is processed into two cell surface associated subunits and a group of proteins. CLCA1 is upregulated by interleukin-9 and regulates the expression of mucins. CLCA1 may provide a therapeutic target to control mucus overproduction in airway disease patients with cystic fibrosis. CLCA2 expression is downregulated in breast cancer, therefore CLCA2 is thought to act as a tumor suppressor in normal cells. CLCA3 (known as Clca3 in mouse) is a structurally divergent member of the CLCA family that does not function as a channel protein. CLCA4 is a CLCA member that is expressed in human rectal mucosa, CLCA5 shows strong expression in eye and spleen, and CLCA6 is primarily expressed in intestine and stomach.


Synonyms: Calcium activated chloride channel 3, Calcium-activated chloride channel regulator family member 3, Chloride channel accessory 3 pseudogene, chloride channel calcium activated 3, Chloride channel calcium activated family member 3, Clca1, Clca2, CLCA3P, Gob 5, Gob-5, Gob5, hCLCA3, mCLCA3, MGC143984, MGC143985.
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months