CD3 anticorps (CD3) (AA 20-70) (HRP)

Details for Product anti-CD3 Antibody No. ABIN1712649, Fournisseur: Connectez-vous pour afficher
Antigène
  • CD3
  • CD3d molecule, delta (CD3-TCR complex)
  • CD3e molecule, epsilon (CD3-TCR complex)
  • DNA segment, Chr 9, MRC UK Mouse Genome Centre 45 expressed
  • CD3D
  • CD3E
  • D9Mgc45e
Épitope
AA 20-70
11
11
10
9
5
4
3
2
1
1
1
1
1
1
1
Reactivité
Porc
796
282
83
43
39
32
30
16
15
14
13
11
10
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
3
2
1
1
Hôte
Lapin
887
179
62
43
22
1
Clonalité
Polyclonal
Conjugué
Cet anticorp CD3 est conjugé à/à la HRP
158
120
93
65
30
23
22
21
21
20
16
15
13
12
12
10
8
8
8
8
8
8
7
7
6
5
5
5
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
952
259
213
149
126
123
109
108
77
48
19
16
12
11
11
10
10
7
7
5
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
1
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from pig CD3E
Isotype IgG
Purification Purified by Protein A.
Autre désignation CD3 (CD3 Antibody Extrait)
Sujet

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Subcellular location: Extracellular

Synonyms: CD3, T-cell surface glycoprotein CD3 epsilon chain, CD3e

ID gène 397455
UniProt Q7YRN2
Domaine de recherche CD Antigens, Surface Receptors of Immune Cells
Indications d'application IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months